Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 9/20 | 0.54 |
| ▸ | F2 | P00734 | 7/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.49 |
| ▸ | KLK1 | P06870 | 7/20 | 0.49 |
| ▸ | F10 | P00742 | 3/20 | 0.48 |
| ▸ | F7 | P08709 | 3/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | F9 | P00740 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434772 | 0.88 | F11 (0.55) | F11F2KLKB1KLK1F10 | |
| SCHEMBL6434756 | 0.88 | F11 (0.55) | F11F2KLKB1KLK1F10 | |
| SCHEMBL6436504 | 0.88 | F11 (0.54) | F11F2KLKB1KLK1F10 | |
| SCHEMBL6436505 | 0.88 | F11 (0.54) | F11F2KLKB1KLK1F10 | |
| SCHEMBL6438353 | 0.87 | F11 (0.53) | F11F2KLKB1KLK1F10 | |
| SCHEMBL6438358 | 0.87 | F11 (0.53) | F11F2KLKB1KLK1F10 | |
| SCHEMBL6439323 | 0.85 | F11 (0.62) | F11F2F10F7F3 | |
| SCHEMBL6435697 | 0.85 | F11 (0.60) | F11F2KLKB1KLK1F10 | |
| SCHEMBL6438813 | 0.85 | F11 (0.62) | F11F2F10F7F3 | |
| SCHEMBL7708322 | 0.85 | F11 (0.60) | F11F2KLKB1KLK1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975600-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | Akzo Nobel N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998047876-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | AKZO NOBEL N.V. (NL) | 1998-10-29 | — | — | WO | disclosed |