Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 11/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082606 | 0.89 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL7571971 | 0.87 | MAPK14 (0.63) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7079282 | 0.84 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL7566944 | 0.82 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL7076132 | 0.81 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL7080441 | 0.78 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11SMN1; SMN2 | |
| SCHEMBL5174459 | 0.78 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7075155 | 0.78 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL7080485 | 0.76 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL7079512 | 0.76 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |