Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | QDPR | P09417 | 1/20 | 0.43 |
| ▸ | KHK | P50053 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9530706 | 0.86 | HTR2C (0.61) | HTR2CKDM4EALDH1A1MAPTSIGMAR1 | |
| SCHEMBL1366798 | 0.86 | HTR2C (0.61) | HTR2CKDM4EALDH1A1MAPTSIGMAR1 | |
| SCHEMBL19297061 | 0.85 | HTR2C (0.53) | HTR2CKDM4EALDH1A1MAPTSIGMAR1 | |
| SCHEMBL24727966 | 0.83 | HTR2C (0.50) | HTR2CKDM4EALDH1A1MAPTSIGMAR1 | |
| SCHEMBL4700645 | 0.82 | HTR1A (0.50) | HTR2CKDM4EALDH1A1MAPTSIGMAR1 | |
| SCHEMBL26530981 | 0.82 | HTR2A (0.44) | HTR2CKDM4EALDH1A1MAPTSIGMAR1 | |
| SCHEMBL6075589 | 0.80 | HTR2C (0.55) | HTR2CKDM4EALDH1A1MAPTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL4930633 | 0.80 | HTR2C (0.46) | HTR2CKDM4EALDH1A1MAPTSIGMAR1 | |
| SCHEMBL4688602 | 0.80 | HTR2C (0.46) | HTR2CKDM4EALDH1A1MAPTSIGMAR1 | |
| SCHEMBL7865138 | 0.79 | HTR2C (0.61) | HTR2CKDM4EALDH1A1MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886636-A1 | NOVEL PIPERIDINES DERIVED FROM 1-/(PIPERAZIN-1-YL)ARYL(OXY/AMINO)CARBONYL/-4-ARYL-PIPERIDINE AS SELECTIVE 5-HT-1D.BETA. RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997028140-A1 | NOVEL PIPERIDINES DERIVED FROM 1-/(PIPERAZIN-1-YL)ARYL(OXY/AMINO)CARBONYL/-4-ARYL-PIPERIDINE AS SELECTIVE 5-HT1Db RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 1997-08-07 | — | — | WO | disclosed |