SCHEMBL7567060

SCHEMBL7567060

CC(C(=O)O)=C(N)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
ALOX15 P16050 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
LDHA P00338 1/20 0.33
LDHB P07195 1/20 0.33
ACHE P22303 1/20 0.30
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21001300 1.00 LMNA (0.35) LMNAALOX15BLMPMP22LDHA
SCHEMBL28403292 0.76 LMNA (0.37) LMNAALOX15BLMPMP22LDHA
SCHEMBL10661623 0.72 FFAR3 (0.55) LMNAALOX15BLMPMP22LDHA
SCHEMBL105999 0.72 FFAR3 (0.55) LMNAALOX15BLMPMP22LDHA
SCHEMBL105998 0.72 FFAR3 (0.55) LMNAALOX15BLMPMP22LDHA
SCHEMBL141678 0.72 FFAR3 (0.55) LMNAALOX15BLMPMP22LDHA
SCHEMBL10661655 0.72 FFAR3 (0.55) LMNAALOX15BLMPMP22LDHA
SCHEMBL71371 0.72 FFAR3 (0.33) FFAR3LCKFYN
SCHEMBL20843720 0.72 LDHA (0.37) LDHALDHBACHE
SCHEMBL27990717 0.72 FFAR3 (0.33) FFAR3LCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028938-B1 PRODUCTION OF AMINOHALOGENCROTONATES SOLVAY FLUOR & DERIVATE (DE) 2002-07-31 EP disclosed