Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564705 | 0.81 | IDO1 (0.46) | EPHX2SCN9AIDO1DRD2CTSL | |
| SCHEMBL31757665 | 0.78 | DRD2 (0.41) | SCN9AIDO1DRD2CTSLCTSB | |
| SCHEMBL31758027 | 0.78 | DRD2 (0.41) | SCN9AIDO1DRD2CTSLCTSB | |
| SCHEMBL29675261 | 0.76 | EPHX2 (0.79) | EPHX2SCN9AMTNR1ADRD2MTNR1B | |
| SCHEMBL29675335 | 0.76 | EPHX2 (0.79) | EPHX2SCN9AMTNR1ADRD2MTNR1B | |
| SCHEMBL31287305 | 0.76 | EPHX2 (0.79) | EPHX2SCN9AMTNR1ADRD2MTNR1B | |
| SCHEMBL22482343 | 0.76 | EPHX2 (0.79) | EPHX2SCN9AMTNR1ADRD2MTNR1B | |
| SCHEMBL18815112 | 0.76 | IDO1 (0.40) | EPHX2SCN9AIDO1DRD2CTSL | |
| SCHEMBL31501230 | 0.74 | CYP1A2 (0.41) | CTSLCTSK | |
| SCHEMBL22482701 | 0.72 | EPHX2 (0.76) | EPHX2MTNR1ADRD2MTNR1BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072352-A1 | Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |