Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415136 | 0.85 | MAPT (0.41) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL7566425 | 0.82 | MAPT (0.51) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL7566451 | 0.76 | ALDH1A1 (0.50) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL7568879 | 0.76 | MAPT (0.45) | KDM4EMAPTALDH1A1GAANPSR1 | |
| SCHEMBL7566548 | 0.76 | MAPT (0.45) | KDM4EMAPTALDH1A1GAANPSR1 | |
| SCHEMBL7565063 | 0.75 | MAPT (0.41) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL7568097 | 0.75 | TP53 (0.38) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL7568244 | 0.75 | MAPT (0.41) | KDM4EMAPTALDH1A1GAANPSR1 | |
| SCHEMBL7568267 | 0.73 | KMT2A (0.48) | KDM4EMAPTALDH1A1HPGDGAA | |
| SCHEMBL7565816 | 0.73 | KMT2A (0.48) | KDM4EMAPTALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |