Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567203 | 0.85 | KDM4E (0.40) | MAPTKDM4EHTTALDH1A1HPGD | |
| SCHEMBL8411691 | 0.84 | MAPT (0.52) | MAPTKDM4EHTTALDH1A1HPGD | |
| SCHEMBL8413588 | 0.77 | ALDH1A1 (0.55) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8415118 | 0.76 | RAD52 (0.40) | MAPTKDM4EHTTALDH1A1KMT2A | |
| SCHEMBL8411863 | 0.76 | RAD52 (0.43) | MAPTKDM4EHTTALDH1A1NPSR1 | |
| SCHEMBL8415074 | 0.74 | KMT2A (0.49) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8411399 | 0.74 | KMT2A (0.49) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8415046 | 0.73 | AOX1 (0.53) | MAPTKDM4EHTTALDH1A1GAA | |
| SCHEMBL8411181 | 0.72 | RAD52 (0.47) | MAPTKDM4EHTTALDH1A1GAA | |
| SCHEMBL8411626 | 0.72 | RAD52 (0.65) | MAPTKDM4EHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |