Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cyclohexane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | FABP7 | O15540 | 3/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.49 |
| ▸ | FABP3 | P05413 | 2/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7569185 | 0.93 | MEN1 (0.57) | MEN1KMT2AHPGDFABP7FABP5 | |
| Bicarbonate SCHEMBL7575978 | 0.88 | HDAC4 (0.50) | MEN1KMT2AHPGDSLC6A2HDAC4 | |
| SCHEMBL11904658 | 0.88 | MEN1 (0.65) | MEN1KMT2AHPGDSLC6A2ALDH1A1 | |
| SCHEMBL415662 | 0.88 | MEN1 (0.65) | MEN1KMT2AHPGDSLC6A2ALDH1A1 | |
| SCHEMBL12592461 | 0.84 | SLC6A2 (0.56) | MEN1KMT2AHPGDSLC6A2SLC6A4 | |
| SCHEMBL1752024 | 0.84 | SLC6A2 (0.56) | MEN1KMT2AHPGDSLC6A2SLC6A4 | |
| SCHEMBL1752183 | 0.84 | SLC6A2 (0.56) | MEN1KMT2AHPGDSLC6A2SLC6A4 | |
| Ethane SCHEMBL27530005 | 0.83 | MEN1 (0.61) | MEN1KMT2ASLC6A2KCNQ3KCNQ2 | |
| Bicarbonate SCHEMBL4410582 | 0.82 | KMO (0.61) | KMT2AKMOHDAC4ALDH1A1 | |
| Bicarbonate SCHEMBL9436080 | 0.82 | KMO (0.61) | KMT2AKMOHDAC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926118-B1 | Process for the purification of bisphenols and preparation of polycarbonates therefrom | GEN ELECTRIC (US) | 2002-09-11 | — | — | EP | disclosed |
| US-6008315-A | REACTING A PHENOL AND A KETONE TO FORM BISPHENOL IN SOLUTION OR A MIXED SOLUTION OF PHENOL AND BISPHENOL, AND THE IMPROVEMENT COMPRISES FILTERING IN A NONCONTAMINATING, HEAT RESISTANT, REUSABLE CALCINED METAL FILTER | GENERAL ELECTRIC COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0926118-A1 | Process for the purification of bisphenols and preparation of polycarbonates therefrom | GENERAL ELECTRIC COMPANY (US) | 1999-06-30 | — | — | EP | disclosed |