Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262549 | 0.83 | OPRM1 (0.36) | OPRM1OPRD1OPRK1OPRL1GAA | |
| Acetic Acid SCHEMBL21640297 | 0.83 | HSD17B10 (0.41) | HSD17B10OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5280131 | 0.77 | OPRM1 (0.41) | OPRM1OPRD1OPRK1OPRL1GAA | |
| SCHEMBL4437885 | 0.77 | — | — | |
| SCHEMBL28435520 | 0.77 | OPRM1 (0.39) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6062835 | 0.76 | CYP2D6 (0.36) | HSD17B10OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5820159 | 0.76 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1GAA | |
| SCHEMBL17607210 | 0.75 | OPRM1 (0.49) | HSD17B10OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17731291 | 0.75 | OPRM1 (0.49) | HSD17B10OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL15689529 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196165-A2 | AZETIDINE COMPOUNDS IN CNS AND EYE DISEASES | VERNALIS RESEARCH LIMITED (GB) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001007022-A2 | AZETIDINE COMPOUNDS IN CNS AND EYE DISEASES | VERNALIS RESEARCH LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |
| US-4088644-A | N-Acyl-3-azetidinone | SCHERING-CORPORATION (US) | 1978-05-09 | — | — | US | disclosed |