SCHEMBL7567488

SCHEMBL7567488

COc1nc(NC(=O)NS(=O)(=O)c2ccccc2C(F)(F)F)nc(C(F)F)n1.[NaH]

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
SLC22A12 Q96S37 4/20 0.40
GAA P10253 1/20 0.39
ALKBH2 Q6NS38 1/20 0.38
ALKBH3 Q96Q83 1/20 0.38
FTO Q9C0B1 1/20 0.38
TSHR P16473 1/20 0.38
USP2 O75604 1/20 0.37
USP8 P40818 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MMP7 P09237 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7561744 0.99 MAPT (0.43) MAPTALDH1A1KDM4ENPC1SLC22A12
SCHEMBL6829101 0.87 MAPT (0.44) MAPTALDH1A1KDM4ENPC1SLC22A12
SCHEMBL53993 0.86 MAPT (0.45) MAPTALDH1A1KDM4ENPC1SLC22A12
SCHEMBL30116869 0.86 MAPT (0.45) MAPTALDH1A1KDM4ENPC1SLC22A12
SCHEMBL29508588 0.86 MAPT (0.45) MAPTALDH1A1KDM4ENPC1SLC22A12
SCHEMBL2973031 0.85 MAPT (0.44) MAPTALDH1A1KDM4ENPC1SLC22A12
SCHEMBL7180471 0.82 ALDH1A1 (0.50) MAPTALDH1A1KDM4ENPC1SLC22A12
Sulfuric Acid SCHEMBL21381522 0.82 MAPT (0.42) MAPTALDH1A1KDM4ENPC1SLC22A12
SCHEMBL17351950 0.78 MAPT (0.39) MAPTALDH1A1KDM4ENPC1SLC22A12
SCHEMBL2108588 0.78 GAA (0.41) MAPTALDH1A1KDM4ENPC1SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020049321-A1 Herbicidal sulfonylureas, their preparation and use MAYER HORST (DE) 2002-04-25 US disclosed
US-6320046-B1 A 2-AMINO-1,3,5-TRIAZINE AS CHEMICAL INTERMEDIATE; HIGH SELECTIVITY IN SENSITIVE CROPS BASF AKTIENGESELLSCHAFT (DE) 2001-11-20 US disclosed
US-6043196-A Herbicidal sulfonylureas, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 2000-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020049321-A1 Herbicidal sulfonylureas, their preparation and use SLC5A1, DDT, SLC5A2 MAPT 4842/4885ALDH1A1 1171/4885KDM4E 2158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.