Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.37 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | USP8 | P40818 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508588 | 0.81 | MAPT (0.45) | MAPTALDH1A1KDM4ENPC1ALKBH2 | |
| SCHEMBL53993 | 0.81 | MAPT (0.45) | MAPTALDH1A1KDM4ENPC1ALKBH2 | |
| SCHEMBL30116869 | 0.81 | MAPT (0.45) | MAPTALDH1A1KDM4ENPC1ALKBH2 | |
| SCHEMBL6829101 | 0.80 | MAPT (0.44) | MAPTALDH1A1KDM4ENPC1ALKBH2 | |
| SCHEMBL2973031 | 0.80 | MAPT (0.44) | MAPTALDH1A1KDM4ENPC1ALKBH2 | |
| SCHEMBL7561744 | 0.79 | MAPT (0.43) | MAPTALDH1A1KDM4ENPC1ALKBH2 | |
| SCHEMBL7180471 | 0.78 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4ENPC1ALKBH2 | |
| SCHEMBL7567488 | 0.78 | MAPT (0.42) | MAPTALDH1A1KDM4ENPC1ALKBH2 | |
| Sulfuric Acid SCHEMBL21381522 | 0.77 | MAPT (0.42) | MAPTALDH1A1KDM4ENPC1ALKBH2 | |
| SCHEMBL2108588 | 0.74 | GAA (0.41) | MAPTALDH1A1KDM4ENPC1ALKBH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150366191-A1 | ANTIMICROBIAL METHOD BY BLOCKING MANNITOL METABOLISM AND ANTIMICROBIAL COMPOSITION CONTAINING MANNITOL METABOLIC INHIBITOR | Research & Business Foundation Sungkyunkwan University (KR) | 2015-12-24 | — | — | US | claimed |
| US-20150366191-A1 | ANTIMICROBIAL METHOD BY BLOCKING MANNITOL METABOLISM AND ANTIMICROBIAL COMPOSITION CONTAINING MANNITOL METABOLIC INHIBITOR | Research & Business Foundation Sungkyunkwan University (KR) | 2015-12-24 | — | — | US | disclosed |
| US-20150366191-A1 | ANTIMICROBIAL METHOD BY BLOCKING MANNITOL METABOLISM AND ANTIMICROBIAL COMPOSITION CONTAINING MANNITOL METABOLIC INHIBITOR | Research & Business Foundation Sungkyunkwan University (KR) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366191-A1 | ANTIMICROBIAL METHOD BY BLOCKING MANNITOL METABOLISM AND ANTIMICROBIAL COMPOSITION CONTAINING MANNITOL METABOLIC INHIBITOR | PHGDH, MDH2, MDH1 | MAPT 1056/4885ALDH1A1 273/4885KDM4E 3301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.