Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.54 |
| ▸ | DRD2 | P14416 | 7/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773949 | 0.83 | — | — | |
| SCHEMBL29881785 | 0.82 | GRIN2B (0.54) | DRD4DRD2DRD3HTR1AHTR2B | |
| SCHEMBL1885658 | 0.82 | GRIN2B (0.54) | DRD4DRD2DRD3HTR1AHTR2B | |
| SCHEMBL2704956 | 0.81 | SLC6A2 (0.57) | DRD4DRD2DRD3HTR1A | |
| SCHEMBL6862585 | 0.80 | GRIN2B (0.69) | ALDH1A1LMNAPOLB | |
| SCHEMBL2704999 | 0.79 | MAPT (0.47) | ALDH1A1MAPT | |
| SCHEMBL23010434 | 0.78 | HTR3A (0.54) | KDM4EALDH1A1MAPT | |
| SCHEMBL6232404 | 0.78 | KMT2A (0.71) | DRD4DRD2DRD3HTR2B | |
| SCHEMBL8092355 | 0.75 | DRD4 (0.65) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL12385909 | 0.74 | DRD4 (0.77) | DRD4DRD2DRD3HTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233961-A2 | METHOD FOR PRODUCING 5-(1-PIPERAZINYL)-BENZOFURAN-2-CARBOXAMIDE BY TRANSITION METAL-CATALYZED AMINATION | MERCK PATENT GmbH (DE) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001040219-A2 | METHOD FOR PRODUCING 5-(1-PIPERAZINYL)-BENZOFURAN-2-CARBOXAMIDE BY TRANSITION METAL-CATALYZED AMINATION | MERCK PATENT GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |