Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896961 | 0.76 | GBA1 (0.41) | GBA1ALDH1A1 | |
| SCHEMBL27949178 | 0.76 | FAAH (0.35) | — | |
| SCHEMBL9284447 | 0.73 | ALDH1A1 (0.54) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28153842 | 0.68 | NPC1 (0.48) | GBA1KMT2AALDH1A1MAPT | |
| SCHEMBL30498897 | 0.67 | GBA1 (0.36) | GBA1ALDH1A1 | |
| SCHEMBL8530603 | 0.67 | ALDH1A1 (0.47) | GBA1ALDH1A1 | |
| SCHEMBL8530547 | 0.67 | ALDH1A1 (0.47) | GBA1ALDH1A1 | |
| SCHEMBL8533648 | 0.67 | ALDH1A1 (0.47) | GBA1ALDH1A1 | |
| SCHEMBL8531412 | 0.67 | ALDH1A1 (0.47) | GBA1ALDH1A1 | |
| SCHEMBL6928388 | 0.67 | ALDH1A1 (0.47) | GBA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207909-A2 | METHOD FOR COUPLING MOLECULES | MEDICAL RESEARCH COUNCIL (GB) | 2002-05-29 | — | — | EP | claimed |
| WO-2001015737-A2 | METHOD FOR COUPLING MOLECULES | MEDICAL RESEARCH COUNCIL (GB) | 2001-03-08 | — | — | WO | claimed |