⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567760 | 0.82 | — | — | |
| SCHEMBL7573317 | 0.82 | — | — | |
| SCHEMBL7110239 | 0.78 | — | — | |
| SCHEMBL7108515 | 0.78 | — | — | |
| SCHEMBL7111526 | 0.78 | — | — | |
| SCHEMBL7108575 | 0.78 | — | — | |
| SCHEMBL856449 | 0.76 | UBE2M (0.47) | — | |
| SCHEMBL11143056 | 0.75 | ALDH1A1 (0.58) | — | |
| SCHEMBL855736 | 0.73 | — | — | |
| SCHEMBL855668 | 0.73 | UBE2M (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993008161-A1 | SULFONYL UREA AND CARBAMATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-04-29 | — | — | WO | claimed |
| US-20020183384-A1 | Methods of treating nuclear factor-kappa B mediated diseases and disorders | CORNICELLI JOSEPH ANTHONY (US) | 2002-12-05 | — | — | US | disclosed |
| EP-1236468-A1 | Sulfonylaminocarbonyl derivatives for the treatment of nuclear factor-kappa B mediated diseases and disorders | WARNER-LAMBERT COMPANY (US) | 2002-09-04 | — | — | EP | disclosed |
| US-5981595-A | LOWERS BLOOD CHOLESTEROL LEVELS | WARNER-LAMBERT COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| WO-1993008161-A1 | SULFONYL UREA AND CARBAMATE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |