Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 5/20 | 0.51 |
| ▸ | LDHB | P07195 | 3/20 | 0.51 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562075 | 0.82 | MAP1LC3B (0.45) | ALDH1A1KDM4EMAP1LC3BMAPTPKM | |
| SCHEMBL7689744 | 0.81 | MAP1LC3B (0.48) | TP53RECQLSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL7689331 | 0.80 | TP53 (0.48) | TP53RECQLSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL21821885 | 0.78 | MEN1 (0.57) | SMN1; SMN2ALDH1A1LMNAHTTLDHA | |
| SCHEMBL21821946 | 0.75 | TP53 (0.57) | TP53RECQLSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL29582956 | 0.75 | TP53 (0.57) | TP53RECQLSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL427764 | 0.75 | TP53 (0.85) | TP53RECQLSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL7560783 | 0.74 | TP53 (0.56) | TP53RECQLSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL7683629 | 0.72 | DAO (0.35) | PKMHPGD | |
| SCHEMBL7690062 | 0.72 | NPC1 (0.32) | SMN1; SMN2ALDH1A1HTTLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229019-A1 | PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLIC ENAMINONE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |