Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.51 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566503 | 1.00 | RAD52 (0.52) | RAD52SIGMAR1TMEM97SMARCA2AOX1 | |
| SCHEMBL10867471 | 0.89 | RAD52 (0.65) | RAD52SIGMAR1TMEM97SMARCA2AOX1 | |
| SCHEMBL7566429 | 0.89 | RAD52 (0.60) | RAD52SIGMAR1TMEM97SMARCA2AOX1 | |
| Hydrochloric Acid SCHEMBL10866593 | 0.88 | RAD52 (0.67) | RAD52SIGMAR1TMEM97SMARCA2AOX1 | |
| SCHEMBL7566551 | 0.88 | RAD52 (0.53) | RAD52SIGMAR1TMEM97SMARCA2AOX1 | |
| SCHEMBL7568883 | 0.88 | RAD52 (0.53) | RAD52SIGMAR1TMEM97SMARCA2AOX1 | |
| SCHEMBL7573723 | 0.87 | RAD52 (0.46) | RAD52SMARCA2AOX1HDAC1HDAC6 | |
| SCHEMBL8414078 | 0.87 | RAD52 (0.46) | RAD52SMARCA2AOX1HDAC1HDAC6 | |
| SCHEMBL7568080 | 0.86 | AOX1 (0.62) | RAD52SIGMAR1TMEM97SMARCA2AOX1 | |
| SCHEMBL7568106 | 0.86 | SIGMAR1 (0.51) | RAD52SIGMAR1TMEM97HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |