Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32659735 | 0.89 | ALDH1A1 (0.61) | TLR8ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10647975 | 0.86 | TLR8 (0.52) | TLR8ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL15488362 | 0.86 | TLR8 (0.56) | TLR8ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6818967 | 0.82 | GPR3 (0.50) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL28223101 | 0.82 | TLR8 (0.60) | TLR8ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27941270 | 0.81 | TLR8 (0.49) | TLR8ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5318249 | 0.80 | KDM4E (0.72) | TLR8ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2537670 | 0.80 | KDM4E (0.72) | TLR8ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL21633651 | 0.80 | KDM4E (0.72) | TLR8ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5319761 | 0.80 | KDM4E (0.72) | TLR8ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046163-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTI-EPILEPTICS | WACKERNAGEL MICHAEL (DE) | 2002-06-13 | — | — | WO | claimed |