SCHEMBL7568436

SCHEMBL7568436

C=CCN(N)N(CC=C)CC=C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11070461 0.75 ALDH1A1 (0.35) ALDH1A1
SCHEMBL7177724 0.75 ALDH1A1 (0.35) ALDH1A1
Hydrochloric Acid SCHEMBL7717766 0.72 ALDH1A1 (0.33) ALDH1A1
SCHEMBL2417531 0.72
SCHEMBL87764 0.69
Bromide SCHEMBL29011443 0.69 ALDH1A1 (0.32) ALDH1A1
Hydrochloric Acid SCHEMBL10636902 0.67
Bromide SCHEMBL9820146 0.67
Hydrochloric Acid SCHEMBL16568824 0.65 ALDH1A1 (0.33) ALDH1A1
SCHEMBL6153929 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0812192-B1 BENZOTHIOPYRANOINDAZOLES ANTITUMOR AGENTS SANOFI SYNTHELABO (FR) 2002-11-06 EP disclosed
EP-0812192-A4 BENZOTHIOPYRANOINDAZOLES ANTITUMOR AGENTS SANOFI WINTHROP INC (US) 2000-03-08 EP disclosed
EP-0812192-A1 BENZOTHIOPYRANOINDAZOLES ANTITUMOR AGENTS SANOFI WINTHROP, INC. (US) 1997-12-17 EP disclosed
WO-1996026723-A1 BENZOTHIOPYRANOINDAZOLES ANTITUMOR AGENTS SANOFI WINTHROP, INC. (US) 1996-09-06 WO disclosed
US-5532263-A Benzothiopyranoindazole antitumor agents STERLING WINTHROP INC. (US) 1996-07-02 US disclosed