Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 15/20 | 0.59 |
| ▸ | ACE | P12821 | 14/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.43 |
| ▸ | CPA1 | P15085 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567284 | 0.87 | MME (0.63) | MMEACEACE2CPA1ITGB1 | |
| SCHEMBL7568441 | 0.86 | MME (0.58) | MMEACEACE2CPA1 | |
| SCHEMBL8450149 | 0.86 | MME (0.43) | MMEACEHSD17B10LMNARAB9A | |
| SCHEMBL7573798 | 0.84 | MME (0.71) | MMEACEACE2CPA1ITGB1 | |
| SCHEMBL7568452 | 0.84 | MME (0.52) | MMEACEACE2CPA1HSD17B10 | |
| SCHEMBL7566049 | 0.83 | MME (0.69) | MMEACEACE2CPA1CTSB | |
| SCHEMBL7568906 | 0.82 | MME (0.77) | MMEACEACE2CPA1 | |
| SCHEMBL7567517 | 0.82 | MME (0.77) | MMEACEACE2CPA1 | |
| SCHEMBL7567925 | 0.82 | MME (0.77) | MMEACEACE2CPA1 | |
| SCHEMBL7569387 | 0.82 | MME (0.67) | MMEACEACE2CPA1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |