Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 14/20 | 0.52 |
| ▸ | ACE | P12821 | 14/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.43 |
| ▸ | CPA1 | P15085 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568446 | 0.84 | MME (0.59) | MMEACEACE2CPA1LMNA | |
| SCHEMBL8450152 | 0.81 | LMNA (0.41) | MMEACELMNAKMT2ASMN1; SMN2 | |
| SCHEMBL27504886 | 0.73 | MME (0.74) | MMEACEACE2CPA1ITGB1 | |
| SCHEMBL8017298 | 0.73 | MME (0.74) | MMEACEACE2CPA1ITGB1 | |
| SCHEMBL8017294 | 0.73 | MME (0.74) | MMEACEACE2CPA1ITGB1 | |
| SCHEMBL7565183 | 0.72 | MME (0.63) | MMEACEACE2CPA1ITGB1 | |
| SCHEMBL7565186 | 0.72 | MME (0.63) | MMEACEACE2CPA1ITGB1 | |
| SCHEMBL7567446 | 0.71 | MME (0.62) | MMEACEACE2CPA1ITGB1 | |
| SCHEMBL7567451 | 0.71 | MME (0.62) | MMEACEACE2CPA1ITGB1 | |
| SCHEMBL7568441 | 0.70 | MME (0.58) | MMEACEACE2CPA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |