Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.90 |
| ▸ | MMP9 | P14780 | 15/20 | 0.78 |
| ▸ | MMP1 | P03956 | 16/20 | 0.71 |
| ▸ | MMP3 | P08254 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507327 | 1.00 | MMP2 (0.90) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7676418 | 0.95 | MMP2 (1.00) | MMP2MMP9MMP1 | |
| SCHEMBL7445146 | 0.88 | MMP2 (0.77) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7500999 | 0.88 | MMP9 (1.00) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7673801 | 0.86 | MMP2 (0.84) | MMP2MMP9MMP1 | |
| SCHEMBL7998641 | 0.85 | MMP2 (0.79) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7443654 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP1 | |
| SCHEMBL7673809 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7506227 | 0.83 | MMP2 (0.85) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7452355 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001930-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | Abbott Laboratories (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999006361-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 1999-02-11 | — | — | WO | claimed |