SCHEMBL7573789

SCHEMBL7573789

Cc1ccc(-c2ccccc2)c(C[C@H](NC(=O)N(CCC(=O)OCc2ccccc2)CC(C)C)C(=O)O)c1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MME P08473 8/20 0.46
ACE P12821 7/20 0.46
CTSB P07858 1/20 0.43
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
LPAR1 Q92633 2/20 0.40
LMNA P02545 1/20 0.39
CTSL P07711 1/20 0.38
CTSS P25774 1/20 0.38
CTSK P43235 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7573605 0.92 MME (0.47) MMEACECTSBLPAR1
SCHEMBL7573305 0.90 MME (0.45) MMEACECTSBLPAR1
SCHEMBL7570085 0.90 MME (0.47) MMEACECTSB
SCHEMBL7565209 0.90 MME (0.46) MMEACECTSBLPAR1CTSL
SCHEMBL7567834 0.88 MME (0.50) MMEACECTSBLPAR1
SCHEMBL7565217 0.88 ITGA4 (0.44) MMEACECTSBKMT2ACTSL
SCHEMBL7567698 0.84 MME (0.59) MMEACECTSBLPAR1
SCHEMBL7574613 0.83 MME (0.55) MMEACECTSB
SCHEMBL7574618 0.83 MME (0.55) MMEACECTSB
SCHEMBL7567838 0.83 MME (0.66) MMEACECTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0798291-B1 NOVEL 1,3-DIALKYLUREA DERIVATIVES SANTEN PHARMACEUTICAL CO LTD (JP) 2002-09-11 EP disclosed
EP-0798291-A1 NOVEL 1,3-DIALKYLUREA DERIVATIVES SANTEN PHARMACEUTICAL CO., LTD. (JP) 1997-10-01 EP disclosed