Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 16/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381564 | 0.84 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL7572613 | 0.84 | P2RX7 (0.72) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL14160432 | 0.83 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL7568709 | 0.83 | P2RX7 (1.00) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL7571529 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL31424200 | 0.83 | P2RX7 (0.76) | P2RX7 | |
| SCHEMBL7570190 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7573037 | 0.82 | P2RX7 (0.69) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL7572585 | 0.80 | P2RX7 (0.70) | P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL7571551 | 0.80 | P2RX7 (0.66) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | claimed |
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | disclosed |