Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381564 | 0.84 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL7572613 | 0.84 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL7568709 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL31424200 | 0.83 | P2RX7 (0.76) | P2RX7 | |
| SCHEMBL14160432 | 0.83 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL7571529 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7568670 | 0.83 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL7573037 | 0.82 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL7570497 | 0.81 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL6362496 | 0.81 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | claimed |
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | disclosed |