Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568855 | 1.00 | PTPN11 (0.43) | PTPN11NPC1RAB9APLAUPOLB | |
| SCHEMBL7566189 | 0.96 | PTPN11 (0.42) | PTPN11NPC1RAB9APLAUPOLB | |
| SCHEMBL7566182 | 0.96 | PTPN11 (0.42) | PTPN11NPC1RAB9APLAUPOLB | |
| SCHEMBL7564402 | 0.92 | PTPN11 (0.44) | PTPN11NPC1RAB9APLAUPOLB | |
| SCHEMBL7564410 | 0.92 | PTPN11 (0.44) | PTPN11NPC1RAB9APLAUPOLB | |
| SCHEMBL9717709 | 0.89 | NPC1 (0.43) | PTPN11NPC1RAB9APLAUSMN1; SMN2 | |
| SCHEMBL9717707 | 0.89 | NPC1 (0.43) | PTPN11NPC1RAB9APLAUSMN1; SMN2 | |
| SCHEMBL11665171 | 0.87 | KAT8 (0.45) | PTPN11NPC1RAB9A | |
| SCHEMBL5835286 | 0.87 | KAT8 (0.45) | PTPN11NPC1RAB9A | |
| SCHEMBL5835290 | 0.87 | KAT8 (0.45) | PTPN11NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855393-B1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KK (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-0855393-A1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-07-29 | — | — | EP | disclosed |