Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717709 | 1.00 | NPC1 (0.43) | NPC1RAB9APTPN11PLAUCES2 | |
| SCHEMBL5835286 | 0.95 | KAT8 (0.45) | NPC1RAB9APTPN11 | |
| SCHEMBL11665171 | 0.95 | KAT8 (0.45) | NPC1RAB9APTPN11 | |
| SCHEMBL28309260 | 0.95 | KAT8 (0.45) | NPC1RAB9APTPN11 | |
| SCHEMBL5835290 | 0.95 | KAT8 (0.45) | NPC1RAB9APTPN11 | |
| SCHEMBL28309259 | 0.95 | KAT8 (0.45) | NPC1RAB9APTPN11 | |
| SCHEMBL7568855 | 0.89 | PTPN11 (0.43) | NPC1RAB9APTPN11PLAUCYP1A2 | |
| SCHEMBL7568853 | 0.89 | PTPN11 (0.43) | NPC1RAB9APTPN11PLAUCYP1A2 | |
| SCHEMBL7566182 | 0.88 | PTPN11 (0.42) | NPC1RAB9APTPN11PLAUCYP1A2 | |
| SCHEMBL7566189 | 0.88 | PTPN11 (0.42) | NPC1RAB9APTPN11PLAUCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259530-B1 | METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES | CHEMIPRO KASEI KAISHA LTD (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4780541-A | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-10-25 | — | — | US | disclosed |