Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665171 | 1.00 | KAT8 (0.45) | KAT8PLK1PLK3PPARANPC1 | |
| SCHEMBL28309260 | 1.00 | KAT8 (0.45) | KAT8PLK1PLK3PPARANPC1 | |
| SCHEMBL5835290 | 1.00 | KAT8 (0.45) | KAT8PLK1PLK3PPARANPC1 | |
| SCHEMBL28309259 | 1.00 | KAT8 (0.45) | KAT8PLK1PLK3PPARANPC1 | |
| SCHEMBL9717709 | 0.95 | NPC1 (0.43) | NPC1RAB9APTPN11 | |
| SCHEMBL9717707 | 0.95 | NPC1 (0.43) | NPC1RAB9APTPN11 | |
| SCHEMBL7566182 | 0.88 | PTPN11 (0.42) | NPC1RAB9APTPN11 | |
| SCHEMBL7566189 | 0.88 | PTPN11 (0.42) | NPC1RAB9APTPN11 | |
| SCHEMBL7568855 | 0.87 | PTPN11 (0.43) | NPC1RAB9APTPN11 | |
| SCHEMBL7568853 | 0.87 | PTPN11 (0.43) | NPC1RAB9APTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074906-B2 | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-07-11 | — | — | US | disclosed |
| US-20050053562-A1 | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | CIBA SPECIALTY CHEMICALS CORP. | 2005-03-10 | — | — | US | disclosed |
| EP-1451254-A1 | ORGANIC SOLVENT-FREE PROCESS FOR THE PREPARATION OF 2-(2-NITROPHENYLAZO)PHENOLS | Ciba SC Holding AG (CH) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003048257-A1 | ORGANIC SOLVENT-FREE PROCESS FOR THE PREPARATION OF 2-(2-NITROPHENYLAZO)PHENOLS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-06-12 | — | — | WO | disclosed |
| EP-0380840-B1 | Method of preparing 2-phenylbenzotriazoles | CHEMIPRO KASEI KAISHA LTD (JP) | 1995-05-17 | — | — | EP | disclosed |
| US-5262541-A | Reaction with sugar as a reducing agent | FAIRMONT CHEMICAL COMPANY, INC. (US) | 1993-11-16 | — | — | US | disclosed |
| US-5187289-A | Method of preparing 2-phenyl benzotriazoles | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0263905-B1 | METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| US-5104992-A | METHOD OF PREPARING 2-PHENYL BENEZOTHRIAZOLES | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0259530-B1 | METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES | CHEMIPRO KASEI KAISHA LTD (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4943637-A | Method for preparing 2-phenylbenzotriazoles | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| EP-0160246-B1 | A METHOD FOR PRODUCING A 2-PHENYLBENZOTRIAZOLE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-01-24 | — | — | EP | disclosed |
| US-4835284-A | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4780541-A | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-10-25 | — | — | US | disclosed |
| EP-0263905-A1 | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-04-20 | — | — | EP | disclosed |
| EP-0160246-A1 | A method for producing A 2-phenylbenzotriazole | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-11-06 | — | — | EP | disclosed |
| US-4129521-A | Branched chain nonyl and dodecyl isomeric mixtures of 2-(5'-nonyl, or dodecyl-2'-hydroxyphenyl)benzotriazole as UV stabilizers | GAF CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |
| US-4096242-A | ULTRAVIOLET AND HEAT RESISTANCE | GAF CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |
| US-RE29596-E | Branched chain dodecyl isomeric mixtures of 2-(5-dodecyl-2-hydroxy phenyl) benzotriazole as stabilizers for heat and light sensitive materials | GAF CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-3983132-A | Branched chain dodecyl isomeric mixtures of 2-(5-dodecyl-2-hydroxy phenyl) benzotriazole as stabilizers for heat and light sensitive materials | GAF CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050053562-A1 | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | HPD, CYP8B1, CYP3A4 | KAT8 2340/4885PLK1 2271/4885PLK3 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.