SCHEMBL7569600

SCHEMBL7569600

CCOC(=O)NC(=S)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
ALDH1A1 P00352 4/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALOX15 P16050 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4902117 0.88 GAA (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL10566251 0.82 GAA (0.35) MGAMGAASIMGAM2ALDH1A1
SCHEMBL10563632 0.81 HPGD (0.41) MGAMGAASIMGAM2ALDH1A1
SCHEMBL7713280 0.80 GAA (0.55) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8967107 0.79 ACHE (0.42) MGAMGAASIMGAM2ALDH1A1
SCHEMBL10893976 0.79 TRPM8 (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL15706095 0.79
SCHEMBL6967574 0.79
SCHEMBL6967569 0.79
SCHEMBL6958990 0.78 GAA (0.48) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054872-B1 PROCESS FOR PREPARING ARYLOXY- OR ALKOXYTRIAZOLINONES BAYER AG (DE) 2002-09-11 EP disclosed
EP-1054872-A1 PROCESS FOR PREPARING ALKOXYTRIAZOLINONES BAYER AG (DE) 2000-11-29 EP disclosed
WO-1999041243-A1 PROCESS FOR PREPARING ALKOXYTRIAZOLINONES BAYER AKTIENGESELLSCHAFT (DE) 1999-08-19 WO disclosed
US-5917050-A Process for preparing alkoxytriazolinones BAYER CORPORATION (US) 1999-06-29 US disclosed
US-4885246-A Optically active carbacyclin intermediates and processes for the preparation thereof NISSHIN FLOUR MILLING CO., LTD. (JP) 1989-12-05 US disclosed
US-4814468-A Optically active carbacyclin intermediates and processes for the preparation thereof NISSHIN FLOUR MILLING CO., LTD. (JP) 1989-03-21 US disclosed