Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 17/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7579034 | 0.92 | LCK (0.57) | LCKMKNK2 | |
| SCHEMBL7507614 | 0.86 | LCK (0.56) | LCKMKNK2 | |
| SCHEMBL7515352 | 0.82 | LCK (0.67) | LCKMKNK2 | |
| SCHEMBL7593210 | 0.81 | LCK (0.84) | LCKCDK2 | |
| SCHEMBL7506201 | 0.80 | LCK (0.58) | LCKCDK2MKNK2 | |
| SCHEMBL7502002 | 0.78 | LCK (0.66) | LCKMKNK2 | |
| SCHEMBL7570454 | 0.77 | LCK (0.62) | LCKMKNK2 | |
| SCHEMBL7588831 | 0.76 | LCK (0.69) | LCK | |
| SCHEMBL7512884 | 0.75 | LCK (0.51) | LCKMKNK2 | |
| SCHEMBL7506412 | 0.75 | MKNK1 (0.50) | LCKMKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206260-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1206260-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000207-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |