Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 16/20 | 0.57 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569772 | 0.92 | LCK (0.55) | LCKMKNK2 | |
| SCHEMBL7507614 | 0.91 | LCK (0.56) | LCKMKNK2MKNK1 | |
| SCHEMBL7515352 | 0.84 | LCK (0.67) | LCKMKNK2MKNK1 | |
| SCHEMBL7983378 | 0.80 | LCK (0.88) | LCK | |
| SCHEMBL7502002 | 0.80 | LCK (0.66) | LCKMKNK2MKNK1 | |
| SCHEMBL7514449 | 0.79 | LCK (0.61) | LCKMKNK2MKNK1 | |
| SCHEMBL7570454 | 0.79 | LCK (0.62) | LCKMKNK2MKNK1 | |
| SCHEMBL7512884 | 0.77 | LCK (0.51) | LCKMKNK2MKNK1 | |
| SCHEMBL7506412 | 0.77 | MKNK1 (0.50) | LCKMKNK2MKNK1 | |
| SCHEMBL7505733 | 0.76 | LCK (0.54) | LCKMKNK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206260-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1206260-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000207-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |