SCHEMBL7570046

SCHEMBL7570046

CCCNC1=NS(=O)(=O)c2sc(C)cc2N1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
MEN1 O00255 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7077604 0.85 ABCC8 (0.44) ADRA2AADRA2BADRA2C
SCHEMBL7078242 0.85 ADRA2A (0.36) ADRA2AADRA2BADRA2C
SCHEMBL31379135 0.83 MEN1 (0.34) MEN1TSHRCYP2C19RAB9AKMT2A
SCHEMBL7563188 0.79 ABCC8 (0.32) CYP2C19RAB9A
SCHEMBL7079077 0.78 ABCC8 (0.43) ADRA2AADRA2BADRA2C
SCHEMBL7565551 0.78 MEN1 (0.34) MEN1TSHRCYP2C19RAB9AKMT2A
SCHEMBL7074970 0.76 ABCC8 (0.41) MEN1TSHRKMT2A
SCHEMBL7080805 0.76 ABCC8 (0.41) MEN1TSHRKMT2A
SCHEMBL6802723 0.76 ABCC8 (0.41) MEN1TSHRKMT2A
SCHEMBL8478611 0.74 ABCC8 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020119969-A1 Novel process NOVO NORDISK A/S (DK) 2002-08-29 US claimed
US-20020119969-A1 Novel process NOVO NORDISK A/S (DK) 2002-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119969-A1 Novel process CYP3A5, CYP4F2, CYP4F12 ADRA2A 1169/4885ADRA2B 648/4885ADRA2C 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.