Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 6/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526207 | 0.74 | THRB (0.48) | HPRT1ALDH1A1POLB | |
| SCHEMBL7567089 | 0.71 | HPRT1 (0.54) | HPRT1 | |
| SCHEMBL9364441 | 0.70 | HPRT1 (0.60) | HPRT1 | |
| SCHEMBL5258342 | 0.70 | HPRT1 (0.48) | HPRT1ALDH1A1POLB | |
| SCHEMBL7570471 | 0.68 | HPRT1 (0.48) | HPRT1ALDH1A1 | |
| SCHEMBL10507491 | 0.68 | HPRT1 (0.46) | HPRT1ALDH1A1 | |
| SCHEMBL7982326 | 0.67 | HPRT1 (0.51) | HPRT1ALDH1A1 | |
| SCHEMBL7570074 | 0.67 | HPRT1 (0.53) | HPRT1ALDH1A1 | |
| SCHEMBL5250159 | 0.67 | HPRT1 (0.60) | HPRT1 | |
| Hydrochloric Acid SCHEMBL7571975 | 0.67 | HDAC3 (0.48) | HPRT1HDAC3HDAC1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237890-A1 | SYNTHESIS AND METHODS OF USE OF 9-SUBSTITUTED GUANINE DERIVATIVES | Neotherapeutics, Inc. (US) | 2002-09-11 | — | — | EP | claimed |
| WO-2001029039-A1 | SYNTHESIS AND METHODS OF USE OF 9-SUBSTITUTED GUANINE DERIVATIVES | NEOTHERAPEUTICS, INC. (US) | 2001-04-26 | — | — | WO | claimed |
| EP-1237890-A1 | SYNTHESIS AND METHODS OF USE OF 9-SUBSTITUTED GUANINE DERIVATIVES | Neotherapeutics, Inc. (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001029039-A1 | SYNTHESIS AND METHODS OF USE OF 9-SUBSTITUTED GUANINE DERIVATIVES | NEOTHERAPEUTICS, INC. (US) | 2001-04-26 | — | — | WO | disclosed |