Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 8/20 | 0.60 |
| ▸ | NOS1 | P29475 | 6/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PAH | P00439 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL489058 | 0.89 | HPRT1 (0.56) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL3743947 | 0.88 | HPRT1 (0.56) | HPRT1NOS1NOS3NOS2USP2 | |
| SCHEMBL21637016 | 0.83 | HPRT1 (0.57) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL3793007 | 0.83 | HPRT1 (0.58) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL3836268 | 0.83 | HPRT1 (0.61) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL9068090 | 0.82 | HPRT1 (0.58) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL9739844 | 0.82 | HPRT1 (0.60) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL6748740 | 0.82 | HPRT1 (0.57) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL571646 | 0.82 | HPRT1 (0.60) | HPRT1NOS1PNP | |
| SCHEMBL5250159 | 0.82 | HPRT1 (0.60) | HPRT1NOS1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464112-B1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS | GEA FARMACEUTISK FABRIK AS (DK) | 1994-10-05 | — | — | EP | disclosed |
| US-5223619-A | Catalytic cyclization | A/S GEA FARMACEUTISK FABRIK (DK) | 1993-06-29 | — | — | US | disclosed |
| EP-0464112-A1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS. | GEA FARMACEUTISK FABRIK AS (DK) | 1992-01-08 | — | — | EP | disclosed |
| WO-1990011283-A1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS | A/S GEA FARMACEUTISK FABRIK (DK) | 1990-10-04 | — | — | WO | disclosed |