SCHEMBL7570153

SCHEMBL7570153

OC(O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.55
CES1 P23141 2/20 0.55
ACP3 P15309 1/20 0.47
KIF11 P52732 4/20 0.46
TRPV6 Q9H1D0 2/20 0.46
ORAI1 Q96D31 1/20 0.46
ORAI2 Q96SN7 1/20 0.46
ORAI3 Q9BRQ5 1/20 0.46
MGLL Q99685 1/20 0.46
HSD11B1 P28845 1/20 0.44
PDE2A O00408 1/20 0.44
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
GSK3B P49841 1/20 0.43
EPHX2 P34913 1/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
PLAU P00749 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2090829 0.84 CES2 (0.55) CES2CES1ACP3KIF11TRPV6
SCHEMBL29400701 0.84 CES2 (0.55) CES2CES1ACP3KIF11TRPV6
SCHEMBL10392935 0.82 CES2 (0.53) CES2CES1ACP3KIF11TRPV6
SCHEMBL28297606 0.82 CES2 (0.53) CES2CES1ACP3KIF11TRPV6
SCHEMBL24397779 0.80 CES2 (0.57) CES2CES1ACP3KIF11TRPV6
SCHEMBL22539278 0.80 CES2 (0.52) CES2CES1ACP3KIF11TRPV6
SCHEMBL991083 0.80 PTPN5 (0.55) CES2CES1ACP3KIF11TRPV6
SCHEMBL5451341 0.80 PTPN5 (0.55) CES2CES1ACP3KIF11TRPV6
SCHEMBL24397778 0.80 CES2 (0.57) CES2CES1ACP3KIF11TRPV6
SCHEMBL342466 0.80 PTPN5 (0.55) CES2CES1ACP3KIF11TRPV6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11415887-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-08-16 US disclosed
US-20200272048-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-08-27 US disclosed
US-9034798-B2 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions CAPROTEC BIOANALYTICS GMBH (DE) 2015-05-19 US disclosed
US-7700584-B2 antitumor agents; viricides HANGZHOU MINSHENG PHARMACEUTICALS CO., LTD. (CN) 2010-04-20 US disclosed
US-20070191360-A1 antitumor agents; viricides HANGZHOU MINSHENG PHARMACEUTICALS CO., LTD. (CN) 2007-08-16 US disclosed
US-20020146633-A1 FLUORINATED AROMATIC ACETAL POLYMERS AND PHOTOSENSITIVE COMPOSITIONS CONTAINING SUCH POLYMERS KODAK POLYCHROME GRAPHICS L.L.C. 2002-10-10 US disclosed
US-6458503-B1 BLEND WITH DIAZO RESIN; LITHOGRAPHIC PRINTING PLATES; PHOTOPOLYMERIZATION AND CROSSLINKING KODAK POLYCHROME GRAPHICS LLC 2002-10-01 US disclosed
WO-2002073315-A1 FLUORINATED AROMATIC ACETAL POLYMERS AND PHOTOSENSITIVE COMPOSITIONS CONTAINING SUCH POLYMERS KODAK POLYCHROME GRAPHICS COMPANY, LTD. (US) 2002-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191360-A1 antitumor agents; viricides HAVCR2, HMOX1, ZC3HAV1 CES2 1575/4885CES1 117/4885ACP3 4541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.