Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570098 | 0.96 | KIF11 (0.62) | FFAR4FFAR1HDAC1HDAC8CA1 | |
| SCHEMBL28913958 | 0.89 | KIF11 (0.69) | FFAR4HDAC1HDAC8ALDH1A1MAPK1 | |
| SCHEMBL26530291 | 0.86 | GAA (0.68) | FFAR4HDAC1HDAC8ALDH1A1MAPK1 | |
| SCHEMBL95648 | 0.86 | FFAR4 (0.60) | FFAR4HDAC1HDAC8ALDH1A1MAPK1 | |
| SCHEMBL26536541 | 0.86 | FFAR4 (0.64) | FFAR4HDAC1HDAC8MAPK1HDAC3 | |
| SCHEMBL18031172 | 0.86 | HDAC1 (0.63) | FFAR4HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL28570269 | 0.86 | FFAR4 (0.60) | FFAR4HDAC1HDAC8ALDH1A1MAPK1 | |
| SCHEMBL6756075 | 0.86 | FFAR4 (0.68) | FFAR4FFAR1HDAC1HDAC8CA1 | |
| SCHEMBL7570765 | 0.86 | CES1 (0.67) | FFAR4HDAC1HDAC8ALDH1A1HDAC3 | |
| SCHEMBL14601690 | 0.86 | FFAR4 (0.68) | FFAR4FFAR1HDAC1HDAC8CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |