SCHEMBL14601690

SCHEMBL14601690

Cc1ccc(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.68
SMN1; SMN2 Q16637 1/20 0.63
TP53 P04637 2/20 0.62
FFAR1 O14842 1/20 0.62
NPY5R Q15761 1/20 0.62
RORC P51449 1/20 0.61
HDAC1 Q13547 3/20 0.60
HDAC8 Q9BY41 3/20 0.60
HDAC3 O15379 2/20 0.60
HDAC4 P56524 2/20 0.60
HDAC7 Q8WUI4 2/20 0.60
HDAC2 Q92769 2/20 0.60
HDAC10 Q969S8 2/20 0.60
HDAC11 Q96DB2 2/20 0.60
HDAC6 Q9UBN7 2/20 0.60
HDAC9 Q9UKV0 2/20 0.60
HDAC5 Q9UQL6 2/20 0.60
ALDH1A1 P00352 1/20 0.59
KIF11 P52732 1/20 0.57
GFER P55789 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6756075 1.00 FFAR4 (0.68) FFAR4SMN1; SMN2TP53FFAR1NPY5R
SCHEMBL26530291 0.88 GAA (0.68) FFAR4SMN1; SMN2TP53HDAC1HDAC8
SCHEMBL28913958 0.88 KIF11 (0.69) FFAR4SMN1; SMN2TP53NPY5RRORC
SCHEMBL7570513 0.86 FFAR4 (0.64) FFAR4SMN1; SMN2TP53FFAR1HDAC1
SCHEMBL14601688 0.85 RORA (0.64) FFAR4SMN1; SMN2TP53FFAR1HDAC1
SCHEMBL7570765 0.85 CES1 (0.67) FFAR4SMN1; SMN2TP53HDAC1HDAC8
SCHEMBL28570269 0.85 FFAR4 (0.60) FFAR4SMN1; SMN2TP53RORCHDAC1
SCHEMBL26536541 0.85 FFAR4 (0.64) FFAR4SMN1; SMN2TP53HDAC1HDAC8
SCHEMBL18031172 0.85 HDAC1 (0.63) FFAR4SMN1; SMN2TP53HDAC1HDAC8
SCHEMBL95648 0.85 FFAR4 (0.60) FFAR4SMN1; SMN2TP53NPY5RRORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070021509-A1 Phosphate transport inhibitors JOZEFIAK THOMAS H 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021509-A1 Phosphate transport inhibitors SLC34A2, SLC34A1, SLC20A1 FFAR4 2368/4885SMN1; SMN2 4295/4885TP53 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.