SCHEMBL7570518

SCHEMBL7570518

CCCCOC(=O)Nc1cc(NC(=O)O)ccc1C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.66
NPC1 O15118 8/20 0.66
SMN1; SMN2 Q16637 8/20 0.66
HPGD P15428 7/20 0.66
CYP1A2 P05177 3/20 0.66
CYP2C19 P33261 3/20 0.66
CYP2C9 P11712 2/20 0.66
ALDH1A1 P00352 6/20 0.54
KDM4E B2RXH2 3/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
LMNA P02545 4/20 0.53
L3MBTL1 Q9Y468 3/20 0.52
MAPK1 P28482 2/20 0.52
MAPT P10636 2/20 0.52
CASP1 P29466 1/20 0.52
MCL1 Q07820 1/20 0.52
NLRP3 Q96P20 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26886778 0.95 RAB9A (0.60) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL473117 0.94 RAB9A (0.73) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL7563817 0.92 LMNA (0.58) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL12637644 0.91 RAB9A (0.68) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1023753 0.90 RAB9A (0.67) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1955495 0.89 RAB9A (0.66) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1951600 0.89 RAB9A (0.66) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL473269 0.89 RAB9A (0.66) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1022067 0.89 RAB9A (0.66) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1951874 0.89 RAB9A (0.66) RAB9ANPC1SMN1; SMN2HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9175131-B2 Deoxybenzoin-derived anti-flammable polymers UNIVERSITY OF MASSACHUSETTS (US) 2015-11-03 US disclosed
US-20130102754-A1 DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS UNIVERSITY OF MASSACHUSETTS (US) 2013-04-25 US disclosed
EP-0855393-B1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KK (JP) 2002-08-14 EP disclosed
US-5922882-A ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1999-07-13 US disclosed
EP-0855393-A1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1998-07-29 EP disclosed