Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.72 |
| ▸ | MAPK13 | O15264 | 11/20 | 0.72 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.72 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566205 | 0.86 | MAPK14 (0.70) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL6655015 | 0.84 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL7565453 | 0.83 | MAPK14 (0.70) | MAPK14MAPK13MAPK12MAPK11TDP1 | |
| SCHEMBL6655495 | 0.83 | MAPK14 (0.82) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL7563806 | 0.81 | MAPK13 (0.68) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL6658543 | 0.80 | MAPK13 (0.80) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL6657882 | 0.80 | MAPK13 (0.73) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL2197842 | 0.80 | MAPK14 (0.79) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL7079569 | 0.80 | MAPK13 (0.72) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL16634680 | 0.79 | MAPK13 (0.71) | MAPK14MAPK13MAPK12MAPK11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | claimed |
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |