Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451942 | 0.90 | ALDH1A1 (0.50) | HTR6ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL21822255 | 0.85 | ALOX15 (0.47) | ALOX15ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL21822508 | 0.85 | ALOX15 (0.53) | ALOX15ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL21822329 | 0.83 | ALOX15 (0.69) | ALOX15ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL30180875 | 0.83 | ALOX15 (0.69) | ALOX15ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL21822288 | 0.82 | ALOX15 (0.47) | ALOX15ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL7447737 | 0.80 | KDM4E (0.64) | HTR6ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL16943501 | 0.78 | ALDH1A1 (0.71) | HTR6ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL14654018 | 0.78 | ALDH1A1 (0.50) | HTR6ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL3121078 | 0.78 | ALOX15 (0.44) | ALOX15ALDH1A1KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |