Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736458 | 0.80 | SLC13A5 (0.45) | ALDH1A1KDM4ECYP1A2MAPTSLC13A5 | |
| SCHEMBL4583329 | 0.79 | KDM4E (0.57) | ALDH1A1KDM4ECYP1A2MAPTMAPK8 | |
| SCHEMBL30583181 | 0.76 | KDM4E (0.62) | ACP3ALDH1A1KDM4ECYP1A2MAPT | |
| SCHEMBL1983224 | 0.76 | KDM4E (0.62) | ACP3ALDH1A1KDM4ECYP1A2MAPT | |
| SCHEMBL16058003 | 0.75 | ABCB1 (0.47) | ALDH1A1KDM4EMAPK8SLC13A5 | |
| SCHEMBL16058683 | 0.74 | PAX8 (0.42) | MAPK8SLC13A5 | |
| SCHEMBL9845784 | 0.73 | ACP3 (0.47) | ACP3ALDH1A1KDM4E | |
| SCHEMBL29707894 | 0.73 | ACP3 (0.46) | ACP3ALDH1A1KDM4ECYP1A2MAPT | |
| SCHEMBL16057405 | 0.73 | PTGER1 (0.46) | ALDH1A1SLC13A5 | |
| SCHEMBL16056930 | 0.73 | BID (0.44) | ALDH1A1MAPTSLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230352-A2 | INHIBITORS OF VEGETABLE CYSTATHIONIN GAMMA SYNTHASE | Aventis CropScience GmbH (DE) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032849-A2 | INHIBITORS OF VEGETABLE CYSTATHIONIN GAMMA SYNTHASE | AVENTIS CROPSCIENCE GMBH (DE) | 2001-05-10 | — | — | WO | disclosed |