Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736458 | 0.84 | SLC13A5 (0.45) | KDM4ECYP1A2MAPTSLC13A5TDP1 | |
| SCHEMBL5780757 | 0.83 | SLC13A5 (0.58) | KDM4ECYP1A2MAPTAKR1B1SLC13A5 | |
| SCHEMBL4705125 | 0.83 | KDM4E (0.57) | KDM4ECYP1A2MAPTAKR1B1SLC13A5 | |
| SCHEMBL16058003 | 0.79 | ABCB1 (0.47) | KDM4ESLC13A5ALDH1A1MAPK8KMT2A | |
| SCHEMBL7570799 | 0.79 | ACP3 (0.39) | KDM4ECYP1A2MAPTSLC13A5ALDH1A1 | |
| SCHEMBL16058683 | 0.78 | PAX8 (0.42) | SLC13A5MAPK8CYP19A1 | |
| SCHEMBL16057405 | 0.76 | PTGER1 (0.46) | SLC13A5ALDH1A1MEN1KMT2A | |
| SCHEMBL16056930 | 0.76 | BID (0.44) | MAPTSLC13A5ALDH1A1MEN1KMT2A | |
| SCHEMBL16057233 | 0.76 | HTT (0.41) | KDM4ESLC13A5TDP1ALDH1A1MEN1 | |
| SCHEMBL16058696 | 0.76 | SLC13A5 (0.40) | KDM4ECYP1A2MAPTSLC13A5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1952797-A1 | Use of a cosmetic composition comprising NMDA receptor agonists for cosmetic skin treatment | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2008-08-06 | — | — | EP | claimed |
| EP-1800672-A1 | Pharmaceutical composition and the use therof for the treatment of dermatoses | Dr. August Wolff GmbH & Co. (DE) | 2007-06-27 | — | — | EP | claimed |
| EP-1952797-A1 | Use of a cosmetic composition comprising NMDA receptor agonists for cosmetic skin treatment | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2008-08-06 | — | — | EP | disclosed |
| EP-1800672-A1 | Pharmaceutical composition and the use therof for the treatment of dermatoses | Dr. August Wolff GmbH & Co. (DE) | 2007-06-27 | — | — | EP | disclosed |