Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28539564 | 1.00 | CES2 (0.54) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27845641 | 0.98 | CES2 (0.52) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL10481654 | 0.85 | CES2 (0.52) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL2242723 | 0.83 | SMN1; SMN2 (0.52) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27533293 | 0.82 | SMN1; SMN2 (0.50) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9806279 | 0.80 | CYP1B1 (0.51) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6955143 | 0.80 | KDM4E (0.49) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9609512 | 0.80 | TERT (0.57) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5448716 | 0.80 | CES2 (0.52) | CES2CES1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9610760 | 0.80 | CES2 (0.52) | CES2CES1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002051795-A1 | CARBOXAMIDES, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE AND PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |