SCHEMBL7570944

SCHEMBL7570944

C=Cc1[c]c2cc3ccccc3cc2cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.35
TDP1 Q9NUW8 3/20 0.35
ALDH1A1 P00352 4/20 0.35
CYP3A4 P08684 3/20 0.35
HSD17B10 Q99714 3/20 0.35
ALOX15 P16050 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
EGFR P00533 1/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
ALOX12 P18054 1/20 0.35
JAK1 P23458 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5749284 0.82 ERN1 (0.35) CYP2A6TDP1ALDH1A1CYP3A4HSD17B10
SCHEMBL294356 0.81 ALDH1A1 (0.33) CYP2A6TDP1ALDH1A1CYP3A4HSD17B10
SCHEMBL3118152 0.73 HPRT1 (0.46) CYP2A6TDP1ALDH1A1CYP3A4HSD17B10
SCHEMBL15366386 0.73 ALDH1A1 (0.40) CYP2A6TDP1ALDH1A1CYP3A4HSD17B10
SCHEMBL195377 0.72 ALDH1A1 (0.36) CYP2A6TDP1ALDH1A1CYP3A4HSD17B10
SCHEMBL1128294 0.71 CYP1A2 (0.43) CYP2A6TDP1ALDH1A1CYP3A4HSD17B10
SCHEMBL1127747 0.71 CYP2A6 (0.43) CYP2A6TDP1ALDH1A1CYP3A4HSD17B10
SCHEMBL1128123 0.71 CYP2A6 (0.43) CYP2A6TDP1ALDH1A1CYP3A4HSD17B10
SCHEMBL17707233 0.71 ALDH1A1 (0.37) CYP2A6TDP1ALDH1A1CYP3A4HSD17B10
SCHEMBL328771 0.71 CYP2A6 (0.43) CYP2A6TDP1ALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11360387-B2 Silicon-containing underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2022-06-14 US claimed
US-10818493-B2 Silicon-based hardmask ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2020-10-27 US claimed
US-20190115209-A1 SILICON-BASED HARDMASK ROHM & HAAS ELECT MAT (US) 2019-04-18 US claimed
US-20190041751-A1 SILICON-CONTAINING UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-02-07 US claimed
US-10186424-B2 Silicon-based hardmask ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2019-01-22 US claimed
US-20180366319-A1 SILICON-BASED HARDMASK ROHM & HAAS ELECT MAT (US) 2018-12-20 US claimed
US-20180164686-A1 METHOD USING SILICON-CONTAINING UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-06-14 US claimed
EP-1025462-B1 THERMOSETTING POLYESTER ANTI-REFLECTIVE COATINGS FOR MULTILAYER PHOTORESIST PROCESSES BREWER SCIENCE INC (US) 2002-09-11 EP claimed
US-5935760-A ATTACHING LIGHT-ABSORBING GROUPS TO SOME OR ALL OF THE REACTIVE METHYLENE GROUPS (IF PRESENT) AND/OR HYDROXY GROUPS PRESENT ON THE RESIN. AMINOPLAST CURING AGENT, ACID CATALYST BREWER SCIENCE INC. (US) 1999-08-10 US claimed
US-11733609-B2 Silicon-containing underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-08-22 US disclosed
CN-111886326-B Water-soluble metalworking oil and metalworking method 出光兴产株式会社 2023-06-06 CN disclosed
US-11360387-B2 Silicon-containing underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2022-06-14 US disclosed
US-20220081513-A1 POLYALKYLENE GLYCOL COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2022-03-17 US disclosed
US-20210397093-A1 SILICON-CONTAINING UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-12-23 US disclosed
US-20190041751-A1 SILICON-CONTAINING UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-02-07 US disclosed
US-10186424-B2 Silicon-based hardmask ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2019-01-22 US disclosed
US-20180366319-A1 SILICON-BASED HARDMASK ROHM & HAAS ELECT MAT (US) 2018-12-20 US disclosed
US-20180164685-A1 METHOD USING SILICON-CONTAINING UNDERLAYERS ROHM & HAAS ELECT MAT (US) 2018-06-14 US disclosed
US-20180164686-A1 METHOD USING SILICON-CONTAINING UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-06-14 US disclosed
US-5935760-A ATTACHING LIGHT-ABSORBING GROUPS TO SOME OR ALL OF THE REACTIVE METHYLENE GROUPS (IF PRESENT) AND/OR HYDROXY GROUPS PRESENT ON THE RESIN. AMINOPLAST CURING AGENT, ACID CATALYST BREWER SCIENCE INC. (US) 1999-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220081513-A1 POLYALKYLENE GLYCOL COMPOUND ALK, AHR, KCNA1 CYP2A6 2093/4885TDP1 4778/4885ALDH1A1 1665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.