Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | CTSC | P53634 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | GCLC | P48506 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725064 | 0.81 | SLC15A1 (0.42) | SLC15A1DPP7DPP4DPP8DPP9 | |
| SCHEMBL10453722 | 0.80 | SLC15A1 (0.43) | SLC15A1DPP7DPP4DPP8DPP9 | |
| SCHEMBL11697935 | 0.80 | SLC15A1 (0.43) | SLC15A1DPP7DPP4DPP8DPP9 | |
| SCHEMBL2888048 | 0.78 | ESR2 (0.39) | SLC15A1SLC1A1CYP3A4USP2GRIK1 | |
| SCHEMBL28240743 | 0.76 | PTGS1 (0.54) | SLC15A1CA1CA2 | |
| SCHEMBL29019106 | 0.76 | PTGS1 (0.54) | SLC15A1CA1CA2 | |
| SCHEMBL6999774 | 0.76 | SLC15A1 (0.39) | SLC15A1DPP7DPP4DPP8DPP9 | |
| SCHEMBL15417545 | 0.75 | — | — | |
| SCHEMBL246284 | 0.75 | — | — | |
| SCHEMBL30660250 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265921-A1 | CHARGED COMPOUNDS COMPRISING A NUCLEIC ACID BINDING MOIETY AND USES THEREFOR | Genesoft, Inc. (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2002034295-A1 | SYNTHETIC REGULATORY COMPOUNDS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2002-05-02 | — | — | WO | disclosed |
| WO-2001074898-A2 | CHARGED COMPOUNDS COMPRISING A NUCLEIC ACID BINDING MOIETY AND USES THEREFOR | GENESOFT, INC. (US) | 2001-10-11 | — | — | WO | disclosed |