Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HK2 | P52789 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27814309 | 0.87 | SLC15A1 (0.43) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL27587942 | 0.79 | SLC15A1 (0.36) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL29616775 | 0.78 | CRBN (0.40) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL29019106 | 0.78 | PTGS1 (0.54) | SLC15A1PTGS1SLC7A11 | |
| SCHEMBL11888829 | 0.78 | CRBN (0.40) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL28240743 | 0.78 | PTGS1 (0.54) | SLC15A1PTGS1SLC7A11 | |
| SCHEMBL7570955 | 0.78 | SLC15A1 (0.42) | CYP3A4SLC1A1SLC15A1GRIK1GRIK2 | |
| SCHEMBL22306291 | 0.75 | GLS (0.33) | ESR2KDM4EALDH1A1ESR1ADORA3 | |
| SCHEMBL574720 | 0.74 | — | — | |
| SCHEMBL2208197 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383755-B2 | Enzyme-medicated cross-linking of silicone polymers | BROCK UNIVERSITY (CA) | 2013-02-26 | — | — | US | disclosed |
| US-20100283183-A1 | ENZYME-MEDICATED CROSS-LINKING OF SILICONE POLYMERS | BROCK UNIVERSITY (CA) | 2010-11-11 | — | — | US | disclosed |
| WO-2008154731-A1 | ENZYME-MEDIATED CROSS-LINKING OF SILICONE POLYMERS | BROCK UNIVERSITY (CA) | 2008-12-24 | — | — | WO | disclosed |