Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.34 |
| ▸ | CTSB | P07858 | 5/20 | 0.34 |
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062047 | 0.76 | CTSS (0.36) | CTSSCTSBCTSLCTSK | |
| SCHEMBL7571020 | 0.75 | CTSS (0.38) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6063311 | 0.72 | CTSS (0.49) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6063309 | 0.72 | CTSS (0.49) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6061996 | 0.72 | CTSS (0.40) | CTSSCTSBCTSL | |
| SCHEMBL6739784 | 0.70 | CTSS (0.46) | CTSSCTSBCTSLCTSK | |
| SCHEMBL7666715 | 0.70 | CTSS (0.44) | CTSSCTSBCTSLCTSK | |
| SCHEMBL7656057 | 0.70 | CTSS (0.40) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6063314 | 0.70 | CTSS (0.40) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6062055 | 0.69 | CTSS (0.43) | CTSSCTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001019808-A1 | CHEMICAL COMPOUNDS AND COMPOSITIONS AND THEIR USE AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |