Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.40 |
| ▸ | CTSL | P07711 | 5/20 | 0.40 |
| ▸ | CTSB | P07858 | 6/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6063314 | 1.00 | CTSS (0.40) | CTSSCTSLCTSBCTSKADRB1 | |
| SCHEMBL6740847 | 0.87 | ADRB1 (0.41) | CTSSCTSLCTSBCTSKADRB1 | |
| SCHEMBL7656008 | 0.84 | CTSS (0.47) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6063311 | 0.83 | CTSS (0.49) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6063309 | 0.83 | CTSS (0.49) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6739784 | 0.81 | CTSS (0.46) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1557652 | 0.79 | CTSS (0.52) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1557648 | 0.79 | CTSS (0.52) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6062346 | 0.78 | CTSS (0.34) | CTSSADRB1KMT2AADRB2ADRB3 | |
| SCHEMBL7571020 | 0.76 | CTSS (0.38) | CTSSCTSLCTSBCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |