SCHEMBL757105

SCHEMBL757105

C[Si]1(C)CC=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14247237 0.53
SCHEMBL1484178 0.53
SCHEMBL567060 0.48
SCHEMBL9723211 0.46
SCHEMBL25653 0.46
SCHEMBL395630 0.43
SCHEMBL34570 0.41
SCHEMBL102954 0.41
SCHEMBL6918 0.41
SCHEMBL231164 0.41

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080009141-A1 Methods to form SiCOH or SiCNH dielectrics and structures including the same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-01-10 US claimed
US-20260051496-A1 TRUE NANOSCALE ONE AND TWO-DIMENSIONAL ORGANOMETALS FURTHER CONTINUATION PEN THE (US) 2026-02-19 US disclosed
US-20190010289-A1 TRUE NANOSCALE ONE AND TWO-DIMENSIONAL ORGANOMETALS CONTINUATION PEN THE (US) 2019-01-10 US disclosed
EP-3307750-A1 TRUE NANOSCALE ONE AND TWO-DIMENSIONAL ORGANOMETALS Pen, The (US) 2018-04-18 EP disclosed
WO-2016205113-A1 TRUE NANOSCALE ONE AND TWO-DIMENSIONAL ORGANOMETALS PEN THE (US) 2016-12-22 WO disclosed
US-20160362522-A1 TRUE NANOSCALE ONE AND TWO-DIMENSIONAL ORGANOMETALS PEN THE (US) 2016-12-15 US disclosed
US-8329835-B2 Polyethylene compositions having improved properties UNIVATION TECHNOLOGIES, LLC (US) 2012-12-11 US disclosed
US-8211904-B2 Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease Merck, Sharp & Dohme Corp. (US) 2012-07-03 US disclosed
EP-1910364-B1 SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE MERCK SHARP & DOHME (US) 2012-03-21 EP disclosed
US-20110098422-A1 POLYETHYLENE COMPOSITIONS HAVING IMPROVED PROPERTIES UNIVATION TECHNOLOGIES, LLC (US) 2011-04-28 US disclosed
US-20070021454-A1 Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease MERCK SHARP & DOHME LLC 2007-01-25 US disclosed
WO-2007011833-A2 SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE MERCK & CO., INC. (US) 2007-01-25 WO disclosed
US-5300605-A Cross-linkable poly(unsaturated carbosilane) homopolymers and copolymers and method of making same UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1994-04-05 US disclosed
US-5260377-A Crosslinkable carbosilane polymer formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1993-11-09 US disclosed
WO-1993017063-A1 CROSSLINKABLE CARBOSILANE POLYMER FORMULATIONS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1993-09-02 WO disclosed
US-5171792-A Crosslinkable saturated and unsaturated carbosilane polymers and formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-12-15 US disclosed
US-5171810-A CROSSLINKABLE POLY(UNSATURATED CARBOSILANE) COPOLYMERS AND METHODS OF MAKING SAME UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-12-15 US disclosed
US-5169916-A Crosslinkable poly(unsaturated carbosilane) polymers and methods of making same UNIVERSITY OF SOUTH CALIFORNIA (US) 1992-12-08 US disclosed
US-5130390-A Crosslinkable saturated and unsaturated carbosilane polymers and formulations UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1992-07-14 US disclosed
US-4870062-A REDUCED NEPHROTOXICITY SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1989-09-26 US disclosed