Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MYB | P10242 | 1/20 | 0.42 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162214 | 0.89 | ALDH1A1 (0.51) | VCAM1MCL1ALDH1A1LMNAMAPT | |
| SCHEMBL6393406 | 0.82 | PTPRC (0.65) | MCL1ALDH1A1LMNAMAPTPTPRC | |
| SCHEMBL5900973 | 0.80 | VCAM1 (0.49) | VCAM1ALDH1A1LMNAMAPTPTPRC | |
| SCHEMBL26129497 | 0.78 | PTPRC (0.47) | ALDH1A1LMNAMAPTPTPRCMEN1 | |
| SCHEMBL8525124 | 0.78 | VCAM1 (0.53) | VCAM1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL10884561 | 0.77 | MAPT (0.50) | ALDH1A1MAPTPTPRCMEN1KMT2A | |
| SCHEMBL28362435 | 0.77 | TDP1 (0.57) | ALDH1A1MAPTPTPRCSMN1; SMN2MEN1 | |
| Nitrogen SCHEMBL8610156 | 0.76 | CA12 (0.50) | ALDH1A1MAPTPTPRCMEN1KMT2A | |
| SCHEMBL27928935 | 0.75 | PTPRC (0.47) | ALDH1A1MAPTPTPRCMEN1KMT2A | |
| SCHEMBL28257786 | 0.75 | TSHR (0.54) | ALDH1A1LMNAMAPTPTPRCMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | VCAM1 1556/4885MCL1 1726/4885ALDH1A1 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.