SCHEMBL7571391

SCHEMBL7571391

CCOCCOc1ccc(Cl)c(Cl)n1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 4/20 0.40
MAPK14 Q16539 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
KDM4E B2RXH2 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PTGES O14684 4/20 0.35
GAA P10253 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
POLB P06746 1/20 0.34
S1PR4 O95977 3/20 0.34
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
P2RY12 Q9H244 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7570410 0.75 TDP1 (0.36) MAPK14L3MBTL1KDM4EGAATDP1
SCHEMBL13564152 0.74 NCF1 (0.41) NCF1MAPK14L3MBTL1KDM4ESMN1; SMN2
SCHEMBL7588939 0.72 GAA (0.51) NCF1MAPK14L3MBTL1KDM4ESMN1; SMN2
SCHEMBL15485538 0.71 NCF1 (0.39) NCF1L3MBTL1KDM4ESMN1; SMN2TDP1
SCHEMBL6377587 0.69 HTR7 (0.61) NCF1MAPK14L3MBTL1KDM4ESMN1; SMN2
SCHEMBL911440 0.69 HPGD (0.40) SMN1; SMN2TDP1POLBS1PR4PDE3B
SCHEMBL29581181 0.69 HPGD (0.40) SMN1; SMN2TDP1POLBS1PR4PDE3B
SCHEMBL7713782 0.68 NPC1 (0.40) NCF1L3MBTL1KDM4ESMN1; SMN2GAA
SCHEMBL14294218 0.68 KDM4E (0.39) NCF1L3MBTL1KDM4ESMN1; SMN2
SCHEMBL13518500 0.68 MAPT (0.42) NCF1L3MBTL1PTGESPDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020115865-A1 2-methoxyimino-2- (pyridinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring CANADA EMILY J (US) 2002-08-22 US disclosed
US-6432990-B1 FUNGICIDES DOW AGROSCIENCES LLC 2002-08-13 US disclosed
US-6369083-B1 2-methoxyimino-2 (pyrinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring DOW AGROSCIENCES LLC 2002-04-09 US disclosed
WO-2000015635-A1 2-METHOXYIMINO -2-(PYRIDINYLOXYMETHYL) PHENYL ACETAMIDES USEFUL AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2000-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115865-A1 2-methoxyimino-2- (pyridinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring AADAC, MIDEAS, CNPY2 NCF1 4617/4885MAPK14 1423/4885L3MBTL1 2276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.